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Vertex Pharmaceuticals Inc

VRTX•NASDAQ•HEALTHCARESample data
$463.87+0.25 (+0.05%)
Market closed•Prev close $463.62
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Research read

Active interest

Evidence read

Smart-money activity on VRTX this 14d.

Saved May 21, 2026· tracking vs the S&P 500

1 sourceLatest

Analyst estimate

+19.1% ($552.7)

12-month analyst consensus · Source: Alpha Vantage

Support

Industrial Production 102.5 (mild expansion) as of 2026-04-01

Risk

Pending dilution: 8 S-3/S-8 shelf in trailing 90d

Tracking

Day 48 of 30D, +8.4% vs the S&P so far.

What's driving it

  • Smart money
  • Fundamentals
  • Technicals
  • Macro
Set alertReview evidenceFundamentalsTechnicals

vs S&P 500. Past performance does not predict future results. Market research, not investment advice.

Section

Smart Money

Funds, insiders, influencers, and government demand tied to this stock — pulled straight from SEC filings, Form 4s, X posts, and federal award data.

Institutional

Who owns this in size

Live8 holders
  • B

    Q1 2026 13F

    BlackRock holds $10.7B

  • SS

    Q1 2026 13F

    State Street holds $5.2B

  • JC

    Q4 2025 13F

    JPMorgan Chase holds $2.7B

  • BO

    Q1 2026 13F

    Bank of America holds $1.3B

  • FL

    Q1 2026 13F

    FMR LLC holds $902.1M

  • Jim Simons

    Q1 2026 13F

    Jim Simons holds $188.3M

  • Two Sigma

    Q1 2026 13F

    Two Sigma holds $168.9M

  • Millennium

    Q4 2025 13F

    Millennium holds $165.8M

    • Insiders

    What insiders are doing

    Live8 trades

    • Sell· EVP, Chief Reg. & Quality Off.

      Tatsis Ourania sold $787K of VERTEX PHARMACEUTICALS INC / MA · Jul 7

    • Sell· EVP and Chief Legal Officer· Cluster

      Liu Joy sold $364K of VERTEX PHARMACEUTICALS INC / MA · Jun 3

    • Sell· EVP and CMO· Cluster

      Bozic Carmen sold $888K of VERTEX PHARMACEUTICALS INC / MA · Jun 2

    • Sell· EVP and CMO· Cluster

      Bozic Carmen sold $614K of VERTEX PHARMACEUTICALS INC / MA · May 19

    • Sell· EVP, Chief Scientific Officer· Cluster

      Bunnage Mark E. sold $15K of VERTEX PHARMACEUTICALS INC / MA · May 19

    • Sell· EVP and CMO· Cluster

      Bozic Carmen sold $3.1M of VERTEX PHARMACEUTICALS INC / MA · May 14

    Influencers

    What traders are saying

    No data yet

    No influencer mentions in the last 30 days.

    X/Twitter finance posts tracked by AlphaYou

    Govt contracts

    Federal awards tied to this company

    Checking USAspending awards...

    Other smart money signals

    Congress trades, activist stakes, short interest & more

    Live1 item

    • short interest change

      short-volume tape softening: latest 23.6% fell 32.9pp vs 20d avg 56.5%

      Moderate

    Section

    Fundamentals

    Business quality, valuation, analyst expectations, and the EPS quarter-over-quarter chart.

    Fundamentals

    Is the business strong?

    Live

    Valuation

    • P/E31.44
    • Forward P/E27.78
    • P/S10.85
    • P/B6.94

    Quality

    • Profit margin35.5%
    • Operating margin38.1%
    • ROE24.2%
    • ROA12.1%

    Growth

    • Revenue YoY--
    • Earnings YoY--
    • Beta0.29
    • Dividend yield--

    Snapshot

    Quick facts

    Updated Jul 8
    Market cap
    $132.55B
    52-week range
    $362.50 - $531.86
    Volume
    2.96M
    Sector
    HEALTHCARE

    Analysts

    What do analysts expect?

    Live

    Current

    $463.87

    Target

    $552.68

    Earnings

    Did earnings help or hurt?

    Live
    $7.81$1.98$-3.86$-9.69$-15.52Q2 '24Q4 '24Q2 '25Q4 '25Q1 '26
    BeatMissMatchEstimate

    Section

    Technicals

    Price trend, moving averages, 52-week range, and chart behavior.

    Price

    Stock chart

    1read marked
    Prior read1

    Technicals

    Chart health

    Live

    Trailing returns

    • 5d+0.51%
    • 20d+0.02%
    • 60d+1.03%

    Trend vs moving averages

    • vs SMA50+0.42%
    • vs SMA200+3.45%

    52w range position

    $362.5060%$531.86

    Based on daily price data. Options flow and order-book data are not in this chart panel yet.

    Section

    Macro

    Sector rotation, market regime, policy, and event-window context.

    Macro

    Market backdrop

    Live

    • macro regime shift

      VIX 18.1 (mild) as of 2026-05-19

    • macro regime shift

      10y-2y spread 53bps (flattish) as of 2026-05-20

    • macro regime shift

      Industrial Production 102.5 (mild expansion) as of 2026-04-01

    • macro regime shift

      Initial claims 211,000 vs 26w mean (ratio 0.99, neutral)

    • macro regime shift

      CPI YoY 3.95% (hot vs Fed target)

    Section

    News

    Catalysts, filings, and market-moving events when they matter.

    News

    Catalysts and headlines

    Live

    • dilution filing

      Pending dilution: 8 S-3/S-8 shelf in trailing 90d

      Moderate

    • sec comment letter

      Active SEC scrutiny: 2 UPLOAD comment letters in trailing 90d

      Moderate

    Section

    Derivatives

    Options flow, volatility regime, gamma pressure, and positioning when available.

    Derivatives

    Options and positioning

    No data yet

    No derivative pressure found yet.

    Options flow, gamma, and volatility signals show here when available.

    +88.81 (+19.1%) possible upside12 months

    12-month analyst consensus · Source: Alpha Vantage