ADRX: SR ONE CAPITAL MANAGEMENT, LLC discloses securities transactions

By AlphaYouPublished Sep 30, 2026Form 4

Stocks in this disclosure

Reported activity

SR ONE CAPITAL MANAGEMENT, LLC

Reporting filer

SR ONE CAPITAL MANAGEMENT, LLC reported Conversion in ADARx Pharmaceuticals, Inc.: 3334938 units of Common Stock, dated 2026-09-28. The full Form 4 contains 15 transaction entries.

Disclosed: Sep 30, 2026

Reported details

15 entries

All validated entries in this disclosure
Security	Owner	Date	Code	Action	Quantity	Price	Following holdings	Reporting delay	Filed terms and references
Common Stock	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	3334938	Not stated (see footnotes)	3,334,938	2 days	Filed terms security Title: Common Stock transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 3334938 id: F1 transaction Acquired Disposed Code: A shares Owned Following Transaction: 3334938 direct Or Indirect Ownership: I nature Of Ownership: See Note 2 id: F2
Common Stock	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	1113666	Not stated (see footnotes)	4,448,604	2 days	Filed terms security Title: Common Stock transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 1113666 id: F1 transaction Acquired Disposed Code: A shares Owned Following Transaction: 4448604 direct Or Indirect Ownership: I nature Of Ownership: See Note 2 id: F2
Common Stock	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	512897	Not stated (see footnotes)	4,961,501	2 days	Filed terms security Title: Common Stock transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 512897 id: F1 transaction Acquired Disposed Code: A shares Owned Following Transaction: 4961501 direct Or Indirect Ownership: I nature Of Ownership: See Note 2 id: F2
Common Stock	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	P	Purchase	592593	17.00	5,554,094	2 days	Filed terms security Title: Common Stock transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: P equity Swap Involved: false transaction Shares: 592593 transaction Price Per Share: 17.00 transaction Acquired Disposed Code: A shares Owned Following Transaction: 5554094 direct Or Indirect Ownership: I nature Of Ownership: See Note 2 id: F2
Common Stock	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	1538691	Not stated (see footnotes)	1,538,691	2 days	Filed terms security Title: Common Stock transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 1538691 id: F1 transaction Acquired Disposed Code: A shares Owned Following Transaction: 1538691 direct Or Indirect Ownership: I nature Of Ownership: See Note 3 id: F3
Common Stock	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	P	Purchase	414814	17	1,953,505	2 days	Filed terms security Title: Common Stock transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: P equity Swap Involved: false transaction Shares: 414814 transaction Price Per Share: 17 transaction Acquired Disposed Code: A shares Owned Following Transaction: 1953505 direct Or Indirect Ownership: I nature Of Ownership: See Note 3 id: F3
Common Stock	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	1667468	Not stated (see footnotes)	1,667,468	2 days	Filed terms security Title: Common Stock transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 1667468 id: F1 transaction Acquired Disposed Code: A shares Owned Following Transaction: 1667468 direct Or Indirect Ownership: I nature Of Ownership: See Note 4 id: F4
Common Stock	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	169001	Not stated (see footnotes)	1,836,469	2 days	Filed terms security Title: Common Stock transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 169001 id: F1 transaction Acquired Disposed Code: A shares Owned Following Transaction: 1836469 direct Or Indirect Ownership: I nature Of Ownership: See Note 4 id: F4
Common Stock	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	P	Purchase	592593	17	592,593	2 days	Filed terms security Title: Common Stock transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: P equity Swap Involved: false transaction Shares: 592593 transaction Price Per Share: 17 transaction Acquired Disposed Code: A shares Owned Following Transaction: 592593 direct Or Indirect Ownership: I nature Of Ownership: See Note 5 id: F5
Series B Preferred Stock (derivative)	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	3907547	0	0	2 days	Filed terms security Title: Series B Preferred Stock id: F1 transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 3907547 transaction Price Per Share: 0 transaction Acquired Disposed Code: D id: F1 id: F1 underlying Security Title: Common Stock underlying Security Shares: 3334938 shares Owned Following Transaction: 0 direct Or Indirect Ownership: I nature Of Ownership: See Note 2 id: F2
Series B-1 Preferred Stock (derivative)	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	1304883	0	0	2 days	Filed terms security Title: Series B-1 Preferred Stock id: F1 transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 1304883 transaction Price Per Share: 0 transaction Acquired Disposed Code: D id: F1 id: F1 underlying Security Title: Common Stock underlying Security Shares: 1113666 shares Owned Following Transaction: 0 direct Or Indirect Ownership: I nature Of Ownership: See Note 2 id: F2
Series C Preferred Stock (derivative)	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	600962	0	0	2 days	Filed terms security Title: Series C Preferred Stock id: F1 transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 600962 transaction Price Per Share: 0 transaction Acquired Disposed Code: D id: F1 id: F1 underlying Security Title: Common Stock underlying Security Shares: 512897 shares Owned Following Transaction: 0 direct Or Indirect Ownership: I nature Of Ownership: See Note 2 id: F2
Series C Preferred Stock (derivative)	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	1802885	0	0	2 days	Filed terms security Title: Series C Preferred Stock id: F1 transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 1802885 transaction Price Per Share: 0 transaction Acquired Disposed Code: D id: F1 id: F1 underlying Security Title: Common Stock underlying Security Shares: 1538691 shares Owned Following Transaction: 0 direct Or Indirect Ownership: I nature Of Ownership: See Note 3 id: F3
Series B Preferred Stock (derivative)	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	1953773	0	0	2 days	Filed terms security Title: Series B Preferred Stock id: F1 transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 1953773 transaction Price Per Share: 0 transaction Acquired Disposed Code: D id: F1 id: F1 underlying Security Title: Common Stock underlying Security Shares: 1667468 shares Owned Following Transaction: 0 direct Or Indirect Ownership: I nature Of Ownership: See Note 4 id: F4
Series B-1 Preferred Stock (derivative)	SR ONE CAPITAL MANAGEMENT, LLC	2026-09-28	C	Conversion	198019	0	0	2 days	Filed terms security Title: Series B-1 Preferred Stock id: F1 transaction Date: 2026-09-28 transaction Form Type: 4 transaction Code: C equity Swap Involved: false transaction Shares: 198019 transaction Price Per Share: 0 transaction Acquired Disposed Code: D id: F1 id: F1 underlying Security Title: Common Stock underlying Security Shares: 169001 shares Owned Following Transaction: 0 direct Or Indirect Ownership: I nature Of Ownership: See Note 4 id: F4

Common Stock

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 3334938
Price: Not stated (see footnotes)
Following holdings: 3,334,938
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 3334938
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 3334938
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Common Stock

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 1113666
Price: Not stated (see footnotes)
Following holdings: 4,448,604
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1113666
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 4448604
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Common Stock

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 512897
Price: Not stated (see footnotes)
Following holdings: 4,961,501
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 512897
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 4961501
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Common Stock

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: P
Action: Purchase
Quantity: 592593
Price: 17.00
Following holdings: 5,554,094
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: P
equity Swap Involved: false
transaction Shares: 592593
transaction Price Per Share: 17.00
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 5554094
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Common Stock

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 1538691
Price: Not stated (see footnotes)
Following holdings: 1,538,691
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1538691
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 1538691
direct Or Indirect Ownership: I
nature Of Ownership: See Note 3
id: F3

Common Stock

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: P
Action: Purchase
Quantity: 414814
Price: 17
Following holdings: 1,953,505
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: P
equity Swap Involved: false
transaction Shares: 414814
transaction Price Per Share: 17
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 1953505
direct Or Indirect Ownership: I
nature Of Ownership: See Note 3
id: F3

Common Stock

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 1667468
Price: Not stated (see footnotes)
Following holdings: 1,667,468
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1667468
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 1667468
direct Or Indirect Ownership: I
nature Of Ownership: See Note 4
id: F4

Common Stock

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 169001
Price: Not stated (see footnotes)
Following holdings: 1,836,469
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 169001
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 1836469
direct Or Indirect Ownership: I
nature Of Ownership: See Note 4
id: F4

Common Stock

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: P
Action: Purchase
Quantity: 592593
Price: 17
Following holdings: 592,593
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: P
equity Swap Involved: false
transaction Shares: 592593
transaction Price Per Share: 17
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 592593
direct Or Indirect Ownership: I
nature Of Ownership: See Note 5
id: F5

Series B Preferred Stock (derivative)

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 3907547
Price: 0
Following holdings: 0
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Series B Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 3907547
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 3334938
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Series B-1 Preferred Stock (derivative)

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 1304883
Price: 0
Following holdings: 0
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Series B-1 Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1304883
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 1113666
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Series C Preferred Stock (derivative)

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 600962
Price: 0
Following holdings: 0
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Series C Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 600962
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 512897
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Series C Preferred Stock (derivative)

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 1802885
Price: 0
Following holdings: 0
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Series C Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1802885
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 1538691
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 3
id: F3

Series B Preferred Stock (derivative)

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 1953773
Price: 0
Following holdings: 0
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Series B Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1953773
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 1667468
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 4
id: F4

Series B-1 Preferred Stock (derivative)

Owner: SR ONE CAPITAL MANAGEMENT, LLC
Date: 2026-09-28
Code: C
Action: Conversion
Quantity: 198019
Price: 0
Following holdings: 0
Reporting delay: 2 days
Filed terms and references: Filed terms
security Title: Series B-1 Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 198019
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 169001
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 4
id: F4

Purchases, sales, grants and option exercises are different transactions. The reported code identifies the action; it does not establish a motive.

Filing context

Quantities and prices are shown in the units filed. No trade value is inferred from their product.
SR ONE CAPITAL MANAGEMENT, LLC: 10% owner.
F1: Each share of Series B Preferred Stock, Series B-1 Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted on a 1-for-1.1717 reverse stock split basis into shares of Common Stock upon the closing of the Issuer's initial public offering on September 28, 2026, without payment of further consideration. The Preferred Stock has no expiration date.
F2: The securities are directly held by SR One Capital Fund I Aggregator, LP ("SR One Fund I Aggregator"). SR One Capital Partners I, LP ("SR One Partners I") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC ("SR One Capital Management") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Partners I, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.
F3: The securities are directly held by SR One Capital Opportunities Fund I, LP ("SR One Opportunities Fund I"). SR One Capital Opportunities Partners I, LP ("SR One Opportunities Partners I") is the sole general partner of SR One Opportunities Fund I, and SR One Capital Management is the sole general partner of SR One Opportunities Partners I. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Opportunities Partners I, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.
F4: The securities are directly held by SR One Co-Invest III, LLC ("SR One Co-Invest"). SR One Co-Invest III Manager LLC ("SR One Co-Invest Manager") is the managing member of SR One-Co-Invest, and SR One Capital Management is the managing member of SR One Co-Invest Manager. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Co-Invest Manager, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.
F5: The reported securities are held directly by AMZL, LP ("AMZL"). SR One Capital SMA Partners, LP ("SR One SMA Partners") is the general partner of AMZL, and SR One Capital Management is the general partner of SR One SMA Partners. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One SMA Partners, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

Original sources

SEC ownership filing

Prepared automatically from public filing data. Report a correction.

Security

Owner

Date

Code

Action

Quantity

Price

Following holdings

Reporting delay

Filed terms and references

Common Stock

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

3334938

Not stated (see footnotes)

3,334,938

2 days

Filed terms

security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 3334938
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 3334938
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Common Stock

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

1113666

Not stated (see footnotes)

4,448,604

2 days

Filed terms

security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1113666
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 4448604
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Common Stock

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

512897

Not stated (see footnotes)

4,961,501

2 days

Filed terms

security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 512897
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 4961501
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Common Stock

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Purchase

592593

17.00

5,554,094

2 days

Filed terms

security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: P
equity Swap Involved: false
transaction Shares: 592593
transaction Price Per Share: 17.00
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 5554094
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Common Stock

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

1538691

Not stated (see footnotes)

1,538,691

2 days

Filed terms

security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1538691
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 1538691
direct Or Indirect Ownership: I
nature Of Ownership: See Note 3
id: F3

Common Stock

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Purchase

414814

1,953,505

2 days

Filed terms

security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: P
equity Swap Involved: false
transaction Shares: 414814
transaction Price Per Share: 17
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 1953505
direct Or Indirect Ownership: I
nature Of Ownership: See Note 3
id: F3

Common Stock

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

1667468

Not stated (see footnotes)

1,667,468

2 days

Filed terms

security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1667468
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 1667468
direct Or Indirect Ownership: I
nature Of Ownership: See Note 4
id: F4

Common Stock

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

169001

Not stated (see footnotes)

1,836,469

2 days

Filed terms

security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 169001
id: F1
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 1836469
direct Or Indirect Ownership: I
nature Of Ownership: See Note 4
id: F4

Common Stock

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Purchase

592593

592,593

2 days

Filed terms

security Title: Common Stock
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: P
equity Swap Involved: false
transaction Shares: 592593
transaction Price Per Share: 17
transaction Acquired Disposed Code: A
shares Owned Following Transaction: 592593
direct Or Indirect Ownership: I
nature Of Ownership: See Note 5
id: F5

Series B Preferred Stock (derivative)

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

3907547

2 days

Filed terms

security Title: Series B Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 3907547
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 3334938
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Series B-1 Preferred Stock (derivative)

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

1304883

2 days

Filed terms

security Title: Series B-1 Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1304883
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 1113666
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Series C Preferred Stock (derivative)

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

600962

2 days

Filed terms

security Title: Series C Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 600962
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 512897
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 2
id: F2

Series C Preferred Stock (derivative)

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

1802885

2 days

Filed terms

security Title: Series C Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1802885
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 1538691
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 3
id: F3

Series B Preferred Stock (derivative)

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

1953773

2 days

Filed terms

security Title: Series B Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 1953773
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 1667468
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 4
id: F4

Series B-1 Preferred Stock (derivative)

SR ONE CAPITAL MANAGEMENT, LLC

2026-09-28

Conversion

198019

2 days

Filed terms

security Title: Series B-1 Preferred Stock
id: F1
transaction Date: 2026-09-28
transaction Form Type: 4
transaction Code: C
equity Swap Involved: false
transaction Shares: 198019
transaction Price Per Share: 0
transaction Acquired Disposed Code: D
id: F1
id: F1
underlying Security Title: Common Stock
underlying Security Shares: 169001
shares Owned Following Transaction: 0
direct Or Indirect Ownership: I
nature Of Ownership: See Note 4
id: F4

Filing context

Quantities and prices are shown in the units filed. No trade value is inferred from their product.

SR ONE CAPITAL MANAGEMENT, LLC: 10% owner.

F1: Each share of Series B Preferred Stock, Series B-1 Preferred Stock and Series C Preferred Stock (collectively, the "Preferred Stock") automatically converted on a 1-for-1.1717 reverse stock split basis into shares of Common Stock upon the closing of the Issuer's initial public offering on September 28, 2026, without payment of further consideration. The Preferred Stock has no expiration date.

F2: The securities are directly held by SR One Capital Fund I Aggregator, LP ("SR One Fund I Aggregator"). SR One Capital Partners I, LP ("SR One Partners I") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC ("SR One Capital Management") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Partners I, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

F3: The securities are directly held by SR One Capital Opportunities Fund I, LP ("SR One Opportunities Fund I"). SR One Capital Opportunities Partners I, LP ("SR One Opportunities Partners I") is the sole general partner of SR One Opportunities Fund I, and SR One Capital Management is the sole general partner of SR One Opportunities Partners I. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Opportunities Partners I, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

F4: The securities are directly held by SR One Co-Invest III, LLC ("SR One Co-Invest"). SR One Co-Invest III Manager LLC ("SR One Co-Invest Manager") is the managing member of SR One-Co-Invest, and SR One Capital Management is the managing member of SR One Co-Invest Manager. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One Co-Invest Manager, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.

F5: The reported securities are held directly by AMZL, LP ("AMZL"). SR One Capital SMA Partners, LP ("SR One SMA Partners") is the general partner of AMZL, and SR One Capital Management is the general partner of SR One SMA Partners. Simeon George, M.D. is the managing member of SR One Capital Management. Each of SR One SMA Partners, SR One Capital Management and Dr. George may be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein.