M

Madrigal Pharmaceuticals Inc

MDGLNASDAQHEALTHCARE
$480.77+6.49 (+1.37%)
After hoursPrev close $474.28

AlphaYou read

Insider Cluster

LONGLive
14/ 100
WeakScore 14 / 100Saved May 29, 2026

Smart-money signal on MDGL this 14d.

Looks good

Smart-money signal on MDGL this 14d.

Watch risk

Negative ROE (-49.3%) - capital destruction

Changed

Saved May 29, 2026. Day 14 of 30D; +0.4% vs S&P so far.

  • Smart money7.0/40
  • Fundamentals2.0/35
  • Technicals2.0/15
  • Macro3.3/10

Price

Stock chart

1call marked
Prior call1

Snapshot

Quick facts

Updated Jun 12
Market cap
$10.96B
P/E ratio
--
Forward P/E
666.67
Beta
-1.06
52-week range
$275.00 - $615.00
Dividend yield
--
Volume
278.8K
Sector
HEALTHCARE

Analysts

What do analysts expect?

Live

Current

$480.77

Target

$679.29

+198.52 (+41.3%) possible upside12 months

Saved calls

Recent AlphaYou calls for this stock

  • LONGMay 29
    Insider Cluster

    Smart-money signal on MDGL this 14d.

    Public call·Results pending

Smart money

What big buyers and insiders are doing

Live6 items
  • filing nport p fund flow

    JANUS INVESTMENT FUND [Janus Henderson Enterprise Fund] opened position ($122.1M)

    +4.0
  • filing 13f fund flow

    Renaissance Technologies LLC holds $48.8M (13F 2025-12-31)

    +5.0
  • filing 13f fund flow

    Citadel Advisors LLC holds $21.0M (13F 2025-12-31)

    +4.0
  • filing nport p fund flow

    Janus Detroit Street Trust (active ETFs) holds $1.5M (NPORT-P 2026-01-31)

    +4.0
  • filing 13f fund flow

    FMR LLC (Fidelity) holds $255.9M (13F 2025-12-31)

    +3.0
  • short interest change

    short-volume tape softening: latest 46.0% fell 14.3pp vs 20d avg 60.3%

    +2.0

Top trader activity

Pending

Real trader activity will show here once the feed is ready.

BTC Astro risk regime

Pending

A broad risk read. Used only as context, not as the main stock reason.

Who helped?

Sources tied to past calls on this stock

Source types

  • SEC EDGAR NPORT-P

    Source family

    D7

    40

    +2.61%

    62.5% hit

    D15

    5

    +5.75%

    60.0% hit

    D30

    1

    -10.02%

    0.0% hit

Funds, insiders, and filers

Did it work?

How past calls did

Soon

No results yet for this stock.

Results appear 7, 15, and 30 days after a call.

Each row shows what happened after the call. Green means it beat the comparison; red means it lagged.

Source links

Can you check the original source?

LiveRules
100.0%
Linked
1
Items
1
Calls
1
Public calls
Source links1/1
SEC EDGAR NPORT-P1/1 linked
Recent source items
  • SEC EDGAR NPORT-P

    FILING NPORT P FUND FLOW · May 29· source

    linked

Fundamentals

Is the business strong?

Live

Valuation

  • P/E--
  • Forward P/E666.67
  • P/S9.68
  • P/B20.25

Quality

  • Profit margin-27.3%
  • Operating margin-29.8%
  • ROE-49.3%
  • ROA-17.6%

Growth

  • Revenue YoY--
  • Earnings YoY--
  • Beta-1.06
  • Dividend yield--

Technicals

Chart health

Live

Trailing returns

  • 5d-3.76%
  • 20d-8.59%
  • 60d+7.02%

Trend vs moving averages

  • vs SMA50-7.53%
  • vs SMA200-3.55%

52w range position

$275.0059%$615.00

Based on daily price data. Options flow and order-book data are not in this chart panel yet.

Macro

Market backdrop

Live
  • macro regime shift

    VIX 15.7 (low volatility) as of 2026-05-28

    +15.7
  • macro regime shift

    10y-2y spread 46bps (flattish) as of 2026-05-28

    +0.5
  • macro regime shift

    Industrial Production 102.5 (mild expansion) as of 2026-04-01

    +102.5
  • macro regime shift

    Initial claims 215,000 vs 26w mean (ratio 1.01, neutral)

    +1.0
  • macro regime shift

    CPI YoY 3.95% (hot vs Fed target)

    +4.0

Earnings

Did earnings help or hurt?

Live
$0.44$-1.82$-4.07$-6.32$-8.57Q2 '24Q4 '24Q2 '25Q4 '25Q1 '26
BeatMissMatchEstimate

Bull vs bear

What could help or hurt?

Live
  • Bullish view

    • JANUS INVESTMENT FUND [Janus Henderson Enterprise Fund] opened position ($122.1M)
    • Renaissance Technologies LLC holds $48.8M (13F 2025-12-31)
    • Citadel Advisors LLC holds $21.0M (13F 2025-12-31)
    • Janus Detroit Street Trust (active ETFs) holds $1.5M (NPORT-P 2026-01-31)

    Bearish view

    No reasons on this side yet.

Reasons come from smart money, fundamentals, technicals, and macro. Counts show how many reasons sit on each side.

Scorecard

Past call results

vs SPY

S&P 500

3 calls · 1L · 2S

Typical edge

+0.43%

Avg edge

+0.05%

Hit rate

66.7%

Mean return

+0.47%

vs QQQ

Nasdaq-100

3 calls · 1L · 2S

Typical edge

+0.97%

Avg edge

-0.36%

Hit rate

66.7%

Mean return

+0.47%

Results are grouped by stock, direction, and day so the same call is not counted twice.